Controls were from the Dutch PHARMO Database Network and the general population in Denmark.
NIFEDIPINE ER PLUS
Patients with out-of-hospital cardiac arrest due to ventricular fibrillation/tachycardia were enrolled, plus up to five controls per patient matched for age and sex. The analysis was done using data from the Dutch Amsterdam Resuscitation Studies registry (ARREST, 2005-2011) and confirmed in the Danish Cardiac Arrest Registry (DANCAR, 2001-2014), both part of ESCAPE-NET. Standard practice is to start with a lower dose, then give the higher dose if blood pressure or chest pain are not sufficiently reduced. The nifedipine doses most often used and studied in this investigation are 30 mg and 60 mg (90 mg is available but infrequently used) and the amlodipine doses are 5 mg and 10 mg. The study examined if nifedipine and amlodipine, dihydropyridines widely used for high blood pressure and angina, are linked with out-of-hospital cardiac arrest. He said: "The findings need to be replicated in other studies before action should be taken by doctors or patients." ESCAPE-NET was set up to find the causes of these arrhythmias, so they can be prevented.ĭr Hanno Tan, ESCAPE-NET project leader and cardiologist, Academic Medical Centre, Amsterdam, the Netherlands, urged caution when interpreting these results. The heart stops pumping after a cardiac arrhythmia (ventricular fibrillation/tachycardia) this is lethal in minutes if untreated. Sudden cardiac arrest causes around half of cardiac deaths in Europe and one in five natural deaths.
0 kommentar(er)
